Endocrine Abstracts

Background: Hypothyroidism (HT) has been demonstrated to be associated to heart failure (HF) progression.Aim of the study: To evaluate the impact of HT on the progression of HF during a long-term follow-up.Methods: From 2006 to 2015, we evaluated 675 consecutive CHF outpatients (523 males, 64±13 years) in stable clinical conditions (>1 month) and in conventional therapy. They underwent a clinical evaluation, 12-lead ECG, e...

Obestatin is a 23-amino acid amidated peptide that is encoded by the ghrelin gene and was therefore presumed to have regulatory effects on pituitary. However, the limited set of studies performed hitherto suggests that obestatin has no major effect on hormone secretion, in vivo or in vitro, from rodent pituitary, whereas no comparable data is still available on primates. Here, primary pituitary cell cultures from a non-human primate (baboon; Papio anubis) served ...